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MutaREAL® ACE, DNA (e.g. whole blood, cheek swab), PCR


SKU: KF290096. Categories: , , .
Description

For  analysis  of  the detect the insertion / deletion (I/D) DNA polymorphism  in  the  intron  16  of  the  ACE  gene coding for the humanangiotensin converting enzyme.  The  insertion  itself  corresponds  to an alu repetitive sequence.

The angiotensin converting  enzyme  (ACE)  is  the  most  important  regulator  of  the  renin/ angiotensin/  aldosteron  system  (RAAS).  The  enzyme  converts  angiotensin  1  into  the physiological  active  form  angiotensin  2.  Latter  one  unfolds  its  vasoconstrictive  effect directly into the organs  (heart, kidney,  vessels).  The  insertion/  deletion  polymorphism  in the ACE gene is  associated immediately  at  the  circulating  ACE  level.  Therefore  the  I/D polymorphism influences the risk for cardiovascular complications.

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