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MutaCHIP® TOXO (Detoxification enzymes), in DNA (e.g. whole blood, cheek swab), PCR (20 chips)


SKU: KF390011. Categories: , .
Description

The Toxo test kit is a biomolecular test for the detection of variations in genes, which protect the body from side effects and intoxications, caused by drugs or foreign substances. The examined genetic variations are associated with the biotransformation of xenobiotics and their transport out off the cell, the antioxidative system and the efficacy and the therewith connected side effects of drugs. Genomic DNA is used for the analysis by means of a DNA macroarray.

The following mutations and polymorphisms are analysed: CYP1A1, CYP1A2, CYP2C9, CYP2C19, CYP3A5, CYP3A4, CYP2B6, VKORC1, GSTM1, GSTT1, GSTP1, NAT2, COMT, SOD2, MDR1, CYBA, MTHFR, Factor V, Factor II.

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